parameters |
Time |
min |
max |
mean |
SD |
Age (Yrs.) |
|
65 |
92 |
73/38 |
98/6 |
Systolic BP (mmHg) |
Pre |
115 |
155 |
134/85 |
96/8 |
Post |
100 |
150 |
122/16 |
8/9 |
|
Δ |
0 |
50 |
12/69 |
71/9 |
|
Diastolic BP(mmHg) |
Pre |
65 |
95 |
79/41 |
19/5 |
Post |
60 |
90 |
74/66 |
78/5 |
|
Δ |
0 |
20 |
4/75 |
84/4 |
|
HR (Per min) |
Pre |
48 |
85 |
71/45 |
39/7 |
Post |
52 |
90 |
77/05 |
89/6 |
|
Δ |
0 |
32 |
5/6 |
92/4 |
*BP: Blood Pressure, HR: Heart Rate
Table 1: Demographic and clinical characteristics of patients before and after intervention
Parameters |
Time |
Intervention |
Mean ± SD |
P-value( A Vs C) |
P-value( B Vs C) |
P-value (A Vs B) |
Systolic BP (mmHg) |
Pre |
ondansetron |
134/45 ±9/84 |
0/68 |
0/84 |
0/84 |
dexamethasone |
134/87 ±9/3 |
|||||
Control |
135/25 ±7/84 |
|||||
Post |
ondansetron |
124/5 ±9/52 |
0/001 |
0/001 |
0/001 |
|
dexamethasone |
124/62 ± 8/5 |
|||||
Control |
117/37 ±9/73 |
|||||
Diastolic BP(mmHg) |
Pre |
ondansetron |
78/87 ±5/82 |
0/57 |
0/73 |
0/43 |
dexamethasone |
79/87 ±5/6 |
|||||
Control |
79/5 ±4/05 |
|||||
Post |
ondansetron |
74/87 ±5/6 |
0/03 |
0/001 |
0/15 |
|
dexamethasone |
76/75±6/05 |
|||||
Control |
72/37±4/93 |
|||||
HR (Per min) |
Pre |
ondansetron |
75/42 ±7/84 |
0/06 |
0/59 |
0/21 |
dexamethasone |
77/5 ±7/07 |
|||||
Control |
78/25 ±5/73 |
|||||
Post |
ondansetron |
70/97 ±8/51 |
0/61 |
0/04 |
0/21 |
|
dexamethasone |
73/25 ±7/55 |
|||||
Control |
70/15 ±8/51 |
Table 2: Investigating the difference between intervention groups in terms of blood pressure and heart rate factors before and after drug administration
Parameters |
Intervention |
Mean ± SD |
P-value( A Vs C) |
P-value( B Vs C) |
P-value (A Vs B) |
Δ Systolic BP (mmHg) |
ondansetron |
9/95 ±8/04 |
0/001 |
0/001 |
0/86 |
dexamethasone |
10/25 ±7/15 |
||||
Control |
17/87 ±11/42 |
||||
Δ Diastolic BP(mmHg) |
ondansetron |
4± 3/43 |
0/005 |
0/005 |
0/29 |
dexamethasone |
3/12 ±4.03 |
||||
Control |
7/12±5/87 |
||||
HR (Per min) Δ |
ondansetron |
4/45±3/66 |
0/005 |
0/001 |
0/79 |
dexamethasone |
4/25±3/31 |
||||
Control |
8/1 ±6/31 |
Table 3: Examining the difference between groups from the perspective of differences in blood pressure and heart rate factors before and after intervention
Parameters |
Intervention |
N (%) |
P-value( A Vs C) |
P-value( B Vs c) |
P-value (A Vs B) |
Atropine |
ondansetron |
1(2.5) |
0/02 |
0/02 |
0/99 |
dexamethasone |
1(2.5) |
||||
Control |
8(20) |
||||
Ephedrine |
ondansetron |
1(2.5) |
0/006 |
0/006 |
0/69 |
dexamethasone |
1(2.5) |
||||
Control |
10(25) |
||||
Table 4: Examining the difference between the intervention groups in terms of atropine and ephedrine administration
Tables at a glance