Value

Reference range

Complete blood count

WBC: 9.2 × 109/L

3.5-10 × 109/L

Neutrophils: 68.3%

40-75%

Lymphocytes: 22.6%

20-45%

Monocytes: 8.2%

4-12%

Eosinophils: 0.3%

0-7%

Metabolic panel

Sodium: 141 mmol/L

135-145 mmol/L

Potassium: 4.3 mmol/L

3.5-5.3 mmol/L

BUN: 13 mg/dL

6-23 mg/dL

Calcium: 9.5 mg/dL

8.6-10.4 mg/dL

Ammonia: 17 µmol/L

11-51 µmol/L

B12: 504 pg/mL

232-1,245 pg/mL

Folate: 18.8 ng/mL

> 4 ng/mL

Autoimmunity

ESR: 25 mm/hr

< 29 mm/hr

CRP: 4.3 mg/L

< 8 mg/L

ANA: 1:80

< 1:40

Ro/SSA, La/SSB, Smith, RNP, Scl-70, JO-1: Negative

Negative

Anti-PR3, Anti-MPO: Negative

Negative

Serum

HIV Ab: Negative

Negative

RPR: Negative

Negative

Lyme Ab: Negative

Negative

CSF cell count

WBC: 1 cells/mm3

0-5 cells/mm3

RBC: 8 cells/mm3

0 cells/mm3

CSF cytology

Rare scattered mononuclear cells, mostly benign lymphocytes

CSF analysis

Protein: 79 mg/dL

15-45 mg/dL

CSF/serum glucose ratio: 60%

50-90%

RT-QuIC for PrP: Positive

Negative

Protein 14-3-3: Positive

Negative

T-tau protein: 10,077 pg/mL

0-1,149 pg/mL

CSF microbiology

Gram stain: No organism

Negative

Culture: No growth

Negative

AFB: No growth

Negative

HSV 1-2: Negative

Negative

Enterovirus: Negative

Negative

Cryptococcal Ag: Negative

Negative

Borrelia: Negative

Negative

CSF autoimmune panel

NMDA-R Ab, AMPA-R Ab, DPPX Ab, CASPR2-IgG, LGI1-IgG, GABA-B-R, Ab: Negative

Negative

●Neuropsychiatric disorder plus positive RT-QuIC in CSF or other tissues

OR

●Rapidly progressive dementia; and at least two out of the following clinical features

○Visual or cerebellar signs ○Pyramidal/extrapyramidal signs
○A kinetic mutism