
Figure 1: JOMD-1307 Inhibits PC Cells growth and progression: (A and B) Graphical representation of the therapeutic effect of JOMD-1307 with increasing concentrations (1 to 20μM) on the viability and proliferation of PC-3 and LNCaP prostate cancer cell line for 72 hrs of incubation, that showed significant inhibition from 1μM. (C and D). PC-3 and LNCaP cells IC50 value represented in log concentration of JOMD- 1307 was approximately 2.0μM. Cell proliferation was presented as the percentage of the number of viable cells to that of the control. Each data point shown is the mean ± SD from n=3. (E) Graphical representation of the effect of JOMD-1307 with increasing concentrations (1 to 20μM) on the PNT1A cell line for 72 hrs of incubation, that showed no significant inhibition before 5μM, with low significant inhibition in increasing concentrations (from 5 to 20μM) compared to PC cell lines.
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