Figure 1 miRNA regulate estrogen production mediated by aromatase enzyme activity, and ERa mediated transcriptional activity, co-regulatory proteins and signaling pathways.

miRNA	Target	Function	Ref.
miR-27a	ZBTB10	Hormone response	38
miR-18a, -19b, -20b	p160 and AIBI	E2 response	33
miR-193b	AKR1C2	E2 production	44
miR-21,-15a,-16, -342	Bcl-2 and PTEN	TAM response	39, 40
miR-221/222, -206	β-catenin	Fulvestrant resistance	50
miR-128a	TGFβ-R1	Aromatase inhibitors resistance	54
miR-23b,-24-1, -27b, -29a	ESR1	Dicer activity	47
miR-375	RASD1	Tumor progression	36
miR-145	TP53	Growth inhibition	42
miR-22,-191/425 cluster	ERα	Tumorigenesis	43, 31
miR-17-9p	AIB1 and c-Myc	Metastasis	41
miR-125a	ERBB2	HER2 expression	59
miR-101	Akt	Cell survival	29
miR-17-92	c-Myc	Promote transcription	35
miR-206, -34a	ERα	Proliferation	37, 32
miR-200c	ZEB1/2, Trk/Bmi1	BRCA-1	55
miR-182	BRCA-1	DNA repair	56

Table 1: Lists of miRNA, whose expression regulates drug resistance, transcriptional factors, and other co-regulatory proteins involve in breast cancer metastasis