Figure 1 the concept of sentinel lymph node.
Figure 1 the concept of sentinel lymph node.
Figure 2 Treatment Algorism For clinically negative neck.
The Study |
Type of the study |
No of cN0 patients |
Type of diagnostic procedures |
Type of management of neck |
Recurrence Or failure |
G.B Flach et al -2013 (7) |
Retrospective |
285 |
USgFNAC |
W&S =234 |
W&S =65 |
O'Connor R et al-2013 (8) |
Prospective |
481 |
SLNB |
ND |
12 |
P. W. Poeschl et al- 2012(9) |
Retrospective |
74 |
C.T-MRI |
ND |
13 |
Martin Canis et al;-2012(10) |
Retrospective |
425 |
C.T-MRI |
W&S =223 |
W&S =16 |
Didier & Philippe -2011(11) |
Prospective |
21 |
C.T-MRI |
ND |
2 |
Bart M. Wensing et al-2011(12) |
Retrospective |
197 |
USgFNAC |
W&S |
48 |
David M. Montes et al -2011(13) |
Retrospective |
109 |
C.T-MRI |
W&S= 61 |
W&S=9 |
Civantos et al-2010(14) |
prospective |
140 |
C.T-MRI |
ND |
7 |
B.M Wensing et al-2010(15) |
Retrospective |
224 |
USgFNAC-US |
ND |
40 |
Yuen Apet al -2009(16) |
Prospective |
71 |
USgFNAC-US |
W&S=35 |
W&S=13 |
M. Okura et al-2009(17) |
Prospective |
165 |
C.T-MRI |
W&S=118 |
W&S=25 |
Keski-Säntti H et al-2008(18) |
Prospective |
13 |
SLNB |
W&S=11 |
0 |
Huang et al-2008(19) |
Retrospective |
380 |
C.T-MRI-US |
W&S=556 |
W&S=16 |
E. M.Lype et al-2008(20) |
Retrospective |
161 |
C.T-MRI-US |
ND=119 |
ND=11 |
Borgemeester MC et al-2008(21) |
Retrospective |
163 |
USgFNAC-US |
W&S=37 |
W&S=17 |
Ana Capote et al-2007(22) |
Retrospective |
154 |
C.T-MRI-US |
W&S=67 |
W&S=18 |
H. Keski et al-2006(23) |
Retrospective |
80 |
C.T-MRI-US |
W&S=34 |
W&S=15 |
Ng et al-2006(24) |
Prospective |
134 |
C.T-MRI- [18F]FDG PET-CT |
ND |
0 |
Wensing et al- 2006(25) |
Prospective |
30 |
US followed by [18F]FDG PET-CT |
ND |
6 |
Robert D. Hart et al-2005(26) |
Prospective |
20 |
SLNB |
ND |
0 |
Alexandru & lidia -2004(27) |
Retrospective |
185 |
C.T-MRI |
W&S= 154 |
W&S=99 |
T. Poli et al-2003(28) |
Prospective |
10 |
SLNB |
ND |
0 |
Sato Eida et al-2003(29) |
Prospective |
58 |
Combination CT & US |
W&S |
17 |
Nieuwenhuis EJ et al-2002(30) |
Prospective |
161 |
USgFNAC |
W&S |
34 |
Rodeny J Taylor et al-2001(31) |
Prospective |
9 |
SLNB |
ND |
0 |
Shoaib T et al- 2001(32) |
Prospective |
40 |
SLNB |
ND |
0 |
Michiel W.M et al- 1999(33) |
Prospective |
77 |
USgFNAC |
W&S |
14 |
Table1 studies included in the current systematic review
Type of intervention |
No. of the patients |
Failure or recurrence |
Neck dissection |
2291 |
148 |
Wait and see policy |
1523 |
406 |
Radiotherapy |
11 |
6 |
Combined therapy |
42 |
9 |
Sentinel lymph node biopsy |
734 |
19 |
Ultrasonography-guided cytology (USgFNAC) |
1107 |
236 |
Table2 Type of intervention, no. of patients and failure or recurrence in the studies included in the current systematic review.