Type (NT or TT)	Grade & # of cores	Cells and appearance	L- plastin staining intensity [%]
Normal prostatic tissue	(-); (n=12)	Normal luminal and basal cells with stromal cells; (All cells appear normal)	Luminal and basal and stromal cells positive for LPL. Staining is weak [12 ± 4.2%]
Cancer cells adjacent to normal prostatic tissue (NAT)	Grade 1; (n=2)	Cells appear normal cells One or two clusters of carcinoma cells have been observed	Cells appear different from normal cells that are positive for LPL and stained strongly [5.26 ± 0.8%]
Adenocarcinoma (Malignant)	Grade 1 (n=4)	Cells appear different from normal cells with lumen with luminal cells and normal stromal cells.	Carcinoma cells stained stronger than the normal cells [28.82 ± 4.8%]*
Adenocarcinoma with necrosis (Malignant)	Grades 2 & 3 (n=7)	Cells appear abnormaland poorly differentiated. The number of lumens with luminal epithelial cells stroma is reduced significantly.	LPL staining is stronger [45.9 ± 5.8%]; Stromal staining is weak [<5.0 ± 1.0%]**

Table 1: Microarrays containing prostatic carcinoma and normal tissues were subjected to immunohistochemistry with an antibody against LPL. Cancer adjacent to NAT and adenocarcinoma (grades 1-3) were present in the microarray. The number (n) of cores for each type are indicated in parentheses in the table. Two investigators performed the analysis, and results are provided as percent intensities. *p<0.05 and **p<0.001 vs. staining intensity of normal prostatic tissue. Values are expressed as mean ± SEM. Staining was performed using two different microarrays (Biomax: PR243 and PR243b).

Tables at a glance

Figures at a glance