Figure 1: A: dental tissue explant extruding DPSC; B: a monolayer of spindle-shaped DPSC in tissue culture flask, day 4
Number |
95 |
Age (range) |
61.5 (36-85) |
Gender |
|
Male |
71 |
Female |
24 |
Clinical T stage |
|
1 |
73 |
2 |
5 |
3 |
16 |
4 |
1 |
Histological subtype |
|
Clear cell |
84 |
Non clear cell |
11 |
Nuclear grade |
|
1 |
12 |
2 |
63 |
3 |
20 |
Microscopic venous invasion |
|
+ |
19 |
- |
76 |
Table 1: : Patients demographics and tumor characteristics
|
Serum XIAP value (mean±SE) (pg/ml) |
Significance |
normal (n=55) |
156.2 ± 41.1 |
|
RCC (n=95) |
228.8 ±26.6 |
p<0.001 |
Tumor stage |
||
T1-2 (n=78) |
216.2±24.1 |
|
T3-4 (n=17) |
285.4±97.5 |
p=0.5113 |
Tumor grade |
||
G1(n=10) |
315.8±147.5 |
|
G2 (n=65) |
230.6±25.5 |
p=0.5811 |
G3 (n=20) |
156.2±56.7 |
p=0.3311 |
Table 2: : Correlation analysis of serum XIAP with clinicopathological characteristics
|
|
Univaritate |
|
|
Parameters |
Criteria |
Hazard ratio |
95% CI of HR |
Significance |
Age |
≥60 vs <60 |
1.75337 |
0.75483-4.257487 |
p=0.1918 |
Sex |
M vs F |
1.618086 |
0.63031734-5.6042534 |
p=0.361 |
Stage |
1,2 vs 3,4 |
0.239731 |
0.103084-0.582689 |
p=0.0023 |
Grade |
1.2 vs 3 |
1.291116 |
0.921548-1.57078 |
p=0.1116 |
v factor |
v (+) vs v (-) |
9.212172 |
3.934812-22.53133 |
p<0.0001 |
Serum XIAP |
L vs H |
0.800736 |
0.335802-1.866751 |
p=0.6056 |
|
|
Multivariate |
|
|
Parameters |
Criteria |
Hazard ratio |
95% CI of HR |
Significance |
Stage |
1,2 vs 3,4 |
0.442053 |
0.179094-1.146613 |
p=0.0909 |
Grade |
1.2 vs 3 |
1.117405 |
0.866443-1.335549 |
p=0.3296 |
v factor |
v(+) vs v(-) |
7.131416 |
2.874289-18.19821 |
p<0.0001 |
Table 3: : Cox regression hazards model analysis in all RCC patients
|
|
Univaritate |
|
|
Parameters |
Criteria |
Hazard ratio |
95% CI of HR |
Significance |
Age |
≥60 vs <60 |
1.010572 |
0601055-1.684427 |
p=0.9679 |
Sex |
M vs F |
1.4113147 |
0.4309298-6.301306 |
p=0.5904 |
Stage |
1,2 vs 3,4 |
0.294361 |
0.089938-1.313672 |
p=0.0995 |
v factor |
v (+) vs v (-) |
0.131296 |
0.043282-0.410747 |
p=0.0009 |
Serum XIAP |
L vs H |
0.307582 |
0.06836-1.017535 |
p=0.0123 |
|
|
Multivariate |
|
|
Parameters |
Criteria |
Hazard ratio |
95% CI of HR |
Significance |
v factor |
v(+) vs v(-) |
0.078209 |
0.021376-0.271072 |
p=0.0001 |
Serum XIAP |
L vs H |
1.002249 |
1.000828-1.003429 |
p=0.0041 |
Table 4: : : Cox regression hazards model analysis in grade 1-2 RCC patients
Figure 1: A: dental tissue explant extruding DPSC; B: a monolayer of spindle-shaped DPSC in tissue culture flask, day 4
Tables at a glance
Figures at a glance