Tables at a glance

Table 1

Table 2

Table 3

Table 4

Figures at a glance

Comments

Figure 1

Table 1

Number	95
Age (range)	61.5 (36-85)
Gender
Male	71
Female	24
Clinical T stage
1	73
2	5
3	16
4	1
Histological subtype
Clear cell	84
Non clear cell	11
Nuclear grade
1	12
2	63
3	20
Microscopic venous invasion
+	19
-	76

Table 1: : Patients demographics and tumor characteristics

Table 2

	Serum XIAP value (mean±SE) (pg/ml)	Significance
normal (n=55)	156.2 ± 41.1
RCC (n=95)	228.8 ±26.6	p<0.001
Tumor stage
T1-2 (n=78)	216.2±24.1
T3-4 (n=17)	285.4±97.5	p=0.5113
Tumor grade
G1(n=10)	315.8±147.5
G2 (n=65)	230.6±25.5	p=0.5811
G3 (n=20)	156.2±56.7	p=0.3311

Table 2: : Correlation analysis of serum XIAP with clinicopathological characteristics

Table 3

		Univaritate
Parameters	Criteria	Hazard ratio	95% CI of HR	Significance
Age	≥60 vs <60	1.75337	0.75483-4.257487	p=0.1918
Sex	M vs F	1.618086	0.63031734-5.6042534	p=0.361
Stage	1,2 vs 3,4	0.239731	0.103084-0.582689	p=0.0023
Grade	1.2 vs 3	1.291116	0.921548-1.57078	p=0.1116
v factor	v (+) vs v (-)	9.212172	3.934812-22.53133	p<0.0001
Serum XIAP	L vs H	0.800736	0.335802-1.866751	p=0.6056
		Multivariate
Parameters	Criteria	Hazard ratio	95% CI of HR	Significance
Stage	1,2 vs 3,4	0.442053	0.179094-1.146613	p=0.0909
Grade	1.2 vs 3	1.117405	0.866443-1.335549	p=0.3296
v factor	v(+) vs v(-)	7.131416	2.874289-18.19821	p<0.0001

Table 3: : Cox regression hazards model analysis in all RCC patients

Table 4

		Univaritate
Parameters	Criteria	Hazard ratio	95% CI of HR	Significance
Age	≥60 vs <60	1.010572	0601055-1.684427	p=0.9679
Sex	M vs F	1.4113147	0.4309298-6.301306	p=0.5904
Stage	1,2 vs 3,4	0.294361	0.089938-1.313672	p=0.0995
v factor	v (+) vs v (-)	0.131296	0.043282-0.410747	p=0.0009
Serum XIAP	L vs H	0.307582	0.06836-1.017535	p=0.0123

		Multivariate
Parameters	Criteria	Hazard ratio	95% CI of HR	Significance
v factor	v(+) vs v(-)	0.078209	0.021376-0.271072	p=0.0001
Serum XIAP	L vs H	1.002249	1.000828-1.003429	p=0.0041

Table 4: : : Cox regression hazards model analysis in grade 1-2 RCC patients

FIGURE 1

Figure 1: A: dental tissue explant extruding DPSC; B: a monolayer of spindle-shaped DPSC in tissue culture flask, day 4