Figure 1 “MR-ProANP during exercise test”
Inclusion criteria |
Exclusion criteria |
Age > 18 years |
Off-pump heart surgery |
Planned CABG |
Endocarditis |
Planned valve surgery, alone or in combination with CABG |
Patients with pacemaker or other metal implantations non- compatible with MRI |
|
Planned implantation of pacemaker. |
Table1 Exclusion- and inclusion criteria for the LAACS trial.
|
LAA-closure group |
LAA-open group |
|
Maximum heart rate, beats per minute mean, (SD) |
127 (22) |
121 (14) (p=0,53) |
|
|
Start systolic blood pressure, mmHg, mean, (range),SD |
140 (153-119),10,04 |
135 (189-105), 25,64 (p=0,59) |
|
Max systolic blood pressure, mmHg, mean, (range),SD |
198 (219-158), 22,75 |
190 (211-147), 21,52 (p=0,46) |
BORG scale mean, (SD) |
17 (0,83) |
16 (0,96) |
|
|
Time to max, minutes mean (SD) |
11 (4.17) |
11 (3.55) |
Table2 Results of exercise test grouped according to randomization.
age (years) |
sex |
Left Ventricle Ejection Fraction (%) |
Left Atrium volume/BSA (ml/m2)* |
beta-blocker use |
RAS blockade use |
MR-pro-ANP baseline (pM) |
MR-pro-ANP max. load (pM) |
delta MR-pro-ANP (pM) |
|
CONTROL |
|
|
|
|
|
|
|
|
|
1 |
54 |
m |
50 |
NA |
yes |
no |
75 |
110 |
34 |
2 |
66 |
m |
60 |
32.5 |
no |
no |
118 |
135 |
17 |
3 |
61 |
m |
55 |
33 |
yes |
yes |
202 |
238 |
36 |
4 |
69 |
m |
60 |
>40 |
yes |
yes |
158 |
196 |
38 |
5 |
56 |
m |
60 |
>40 |
yes |
no |
263 |
311 |
48 |
6 |
80 |
f |
55 |
NA |
yes |
no |
245 |
312 |
68 |
7 |
66 |
m |
60 |
NA |
yes |
no |
130 |
146 |
16 |
8 |
76 |
m |
60 |
32.2 |
yes |
yes |
155 |
171 |
16 |
9 |
74 |
m |
60 |
NA |
yes |
no |
159 |
203 |
44 |
10 |
73 |
m |
45 |
NA |
yes |
yes |
130 |
154 |
24 |
CLOSED LAA |
|
|
|
|
|
|
|
|
|
1 |
76 |
f |
60 |
32.3 |
no |
yes |
160 |
219 |
59 |
2 |
53 |
m |
50 |
27.9 |
yes |
no |
54 |
77 |
23 |
3 |
70 |
m |
35 |
34.4 |
yes |
yes |
262 |
290 |
28 |
4 |
55 |
f |
60 |
NA |
yes |
yes |
90 |
110 |
20 |
5 |
72 |
m |
60 |
28 |
no |
yes |
110 |
125 |
14 |
6 |
70 |
m |
55 |
NA |
yes |
no |
306 |
349 |
43 |
7 |
75 |
f |
50 |
NA |
no |
no |
94 |
112 |
18 |
8 |
64 |
m |
45 |
37.6 |
yes |
yes |
72 |
91 |
19 |
9 |
74 |
m |
50 |
28 |
no |
no |
90 |
106 |
16 |
p-values |
0,96 |
0,14 |
0,08 |
0,10 |
0,52 |
0,46 |
0,41 |
0,32 |
Table3 Patient characteristics and MR-pro-ANP levels.