Figure 1 “MR-ProANP during exercise test”

Inclusion criteria

Exclusion criteria

Age > 18 years

Off-pump heart surgery

Planned CABG

Endocarditis

Planned valve surgery, alone or in combination with CABG

Patients with pacemaker or other metal implantations non- compatible with MRI

 

Planned implantation of pacemaker.

Table1 Exclusion- and inclusion criteria for the LAACS trial.

 

LAA-closure group

LAA-open group

Maximum heart rate, beats per minute mean, (SD)

127 (22)

121 (14) (p=0,53)

 

Start systolic blood pressure, mmHg, mean, (range),SD 

140 (153-119),10,04

135 (189-105), 25,64 (p=0,59)

 

Max systolic blood pressure, mmHg, mean, (range),SD

198 (219-158), 22,75

190 (211-147), 21,52 (p=0,46)

BORG scale mean, (SD)

17 (0,83)

16 (0,96)

 

Time to max, minutes mean (SD)

11 (4.17)

11 (3.55)

Table2 Results of exercise test grouped according to randomization.

 

age (years)

sex

Left Ventricle Ejection Fraction (%)

Left Atrium volume/BSA (ml/m2)*

beta-blocker use

RAS blockade use

MR-pro-ANP            baseline           (pM)

MR-pro-ANP            max. load  (pM)

delta                           MR-pro-ANP (pM)

CONTROL

 

 

 

 

 

 

 

 

 

1

54

m

50

NA

yes

no

75

110

34

2

66

m

60

32.5

no

no

118

135

17

3

61

m

55

33

yes

yes

202

238

36

4

69

m

60

>40

yes

yes

158

196

38

5

56

m

60

>40

yes

no

263

311

48

6

80

f

55

NA

yes

no

245

312

68

7

66

m

60

NA

yes

no

130

146

16

8

76

m

60

32.2

yes

yes

155

171

16

9

74

m

60

NA

yes

no

159

203

44

10

73

m

45

NA

yes

yes

130

154

24

CLOSED LAA

 

 

 

 

 

 

 

 

 

 

1

76

f

60

32.3

no

yes

160

219

59

 

2

53

m

50

27.9

yes

no

54

77

23

 

3

70

m

35

34.4

yes

yes

262

290

28

 

4

55

f

60

NA

yes

yes

90

110

20

 

5

72

m

60

28

no

yes

110

125

14

 

6

70

m

55

NA

yes

no

306

349

43

 

7

75

f

50

NA

no

no

94

112

18

 

8

64

m

45

37.6

yes

yes

72

91

19

 

9

74

m

50

28

no

no

90

106

16

p-values

0,96

0,14

0,08

0,10

0,52

0,46

0,41

0,32

Table3 Patient characteristics and MR-pro-ANP levels.