Figure 1
Figure 1
Figure 2
|
GROUP-1 NSTEMI n(%) |
GROUP-2 STEMI n(%) |
p-VALUE |
||
AGE |
>50 |
15 (25 ) |
24(40) |
0.07 |
|
<50 |
45(75) |
36(60) |
|||
SEX |
MALE |
49(64.83) |
44(73.33) |
0.172 |
|
FEMALE |
11(35.17) |
16(26.67) |
|||
SMOKING |
NON SMOKER |
22(36.66) |
28(46.66) |
0.465 |
|
SMOKER |
28(63.34) |
32(53.34) |
|||
ALCOHOL |
NON -ALCOHOL |
48(80) |
38(73.65) |
0.043 |
|
ALCOHOL |
12(20) |
22(26.35) |
|||
PHYSICAL ACTIVITY |
REGULAR |
15(25) |
11(18.33) |
0.375 |
|
INTERMITTENT |
45(75) |
49(81.66) |
|||
WEIGHT (kgs) |
<50 |
13(21.66) |
11(18.33) |
|
|
>50 |
47(78.33) |
49(51.04) |
|||
DM |
NO |
45(75.00) |
45(75.00) |
1.000 |
|
YES |
15(25.0) |
15(25.0) |
|||
BP |
90- 130 |
30(50.0) |
36(60.0) |
0.197 |
|
>130 |
30(50.0) |
22(36.6) |
|||
<90 |
0(0.00) |
1(1.66) |
|||
KILLIP HEMODYNAMI |
NO CLASS |
1(1.66) |
2(3.33) |
0.275 |
|
CLASS 1 |
28(46.6) |
39(65.0) |
|||
CLASS 2 |
14(23.3) |
8(13.33) |
|||
CLASS 3 |
8(13.33) |
5(8.33) |
|||
CLASS 4 |
9(15.0 ) |
6(1.0) |
|||
CHF |
NO |
41(68.33) |
43(71.66) |
0.690 |
|
YES |
19(31.66) |
17(28.33) |
|||
Hemoglobin |
>9 |
57(95.0) |
60(100.0) |
0.122 |
|
<9 |
3(5.00) |
0(0.00) |
|||
Hematocrit |
41-53 |
18(30.0) |
22(36.66) |
0.439 |
|
1>53 |
42(70.0) |
38(63.33) |
|||
Platelet count |
<1.5 |
48(80.00) |
52(86.66) |
0.327 |
|
>4.5 |
12(20.00) |
8(13.33) |
|||
Total leucocyte count |
10000 |
48(80.0) |
42(70) |
0.386 |
|
>10000 |
10(16.66) |
17(28.33) |
|||
<4000 |
2(3.33) |
1(1.66) |
|||
ESR |
MALE<17, FEMALE<25 |
16(26.66) |
35(58.33) |
0.000 |
|
MALE>17, FEMALE>25 |
44(73.33) |
25(41.66) |
|||
GLUCOSE |
UPTO 140 |
51(85.0) |
50(83.33) |
0.636 |
|
>140 |
9(15) |
10(16.66) |
|||
Dyslipidemia
|
NO |
36(60) |
35(58.33) |
0.853 |
|
YES |
24(40) |
25(41.66) |
|||
CRP
|
UPTO 3 |
28(46.66) |
31(51.66) |
0.584 |
|
>3 |
32(53.33) |
29(48.33) |
|||
TR0P0NIN-I |
NEGATIVE |
39(65.0) |
34(56.66) |
0.453 |
|
POSITIVE |
21(35.0) |
25(43.33) |
|||
CK
|
|
43(71.66) |
26(43.33) |
0.002 |
|
|
17(28.33) |
34(56.66) |
|||
CK-MB |
8.5(0.1-267) |
8(0.8-414) |
0.637 |
||
Coagulopathy |
NO |
58(96.66) |
52(86.66) |
0.047 |
|
YES |
2(3.33) |
8(13.33) |
|||
Site of infraction
|
ANTERIOR |
33(55.0) |
33(55.00) |
1.000 |
|
INFERIOR |
26(43.33) |
25(41.66) |
|||
POSTERIOR |
1(1.66) |
2(3.33) |
|||
|
|||||
Table: 1. Baseline characteristics of Study participants
CYTOKINE |
GROUP 1` STEMI Median (Min-Max) |
GROUP 2 NSTEMI Median (Min-Max) |
GROUP 3 CONTROLS Median (Min-Max) |
P –VALUE OVERALL |
1 VS 2 |
1 VS 3 |
2VS3 |
IL 6 -day 0 |
5.16 (0- 304.48) |
1.07 (0 - 261.87 ) |
0.30 (0 -10.83) |
0.0001 |
0.0026 |
0.0000 |
0.0145 |
IL 6- day 3 |
8.26 (0-324.05) |
1.14 (0 -412.46) |
0.30 (0 -10.83) |
0.0001 |
0.0005 |
0.0000 |
0.0152 |
P VALUE |
0.123 |
0.513 |
--- |
--- |
--- |
--- |
--- |
IL 10 -day 0 |
1.87 (0- 143.05) |
1.84 (0 -243.80) |
1.42 (0 -189.16) |
0.8157 |
---- |
--- |
--- |
IL10 –day 3 |
2.96 (0 -143.57) |
2.18 (0 -64.70) |
1.42 (0 -189.16) |
0.1032 |
--- |
--- |
--- |
P VALUE |
0.000 |
0.485 |
--- |
--- |
--- |
--- |
--- |
IL 18 –day 0 |
434.95 (23.93 -4805.13) |
263.08 (0 - 4872.10) |
46.51 ( 0 - 495.81) |
0.0001 |
0.8604 |
0.0000 |
0.0000 |
IL 18- day 3 |
123.73 (0-1935.11) |
108.40 (0-3763.62) |
46.51 ( 0 - 495.81) |
0.0005 |
0.1538 |
0.0025 |
0.0005 |
P VALUE |
0.000 |
0.002 |
--- |
---- |
---- |
---- |
---- |
TNF alpha -day 0 |
33.48 ( 0 - 98.89 ) |
60.68 (0 - 634.43) |
6.37 ( 0 -866.86) |
0.0001 |
0.0000 |
0.0000 |
0.0000 |
TNF alpha-day 3 |
33.48 (9.41 - 216.43 ) |
43.53 (6.61 - 412.46) |
6.37 (0 -866.86) |
0.0001 |
0.0212 |
0.0000 |
0.0000 |
P VALUE |
0.6540 |
0.0088 |
----- |
---- |
----- |
---- |
---- |
Table.2. Correlation of different cytokines