Variables	All subjects n = 534,414
Age, years	63 ą 6
Male, n (%)	229,927 (43%)
Suita score	46 ą 10
Framingham risk score	6.6 ą 2.9
BMI, kg/m2	23.5 ą 3.4
Waist circumference, cm	84 ą 9
Hypertension, n (%)	231,126 (43%)
Systolic BP, mmHg	129 ą 16
Diastolic BP, mmHg	76 ą 11
Dyslipidemia, n (%)	298,946 (56%)
Diabetes mellitus, n (%)	62,189 (12%)
Smoking, n (%)	82,391 (15%)
Biochemical data
eGFR, ml/min/1.73m2	76 ą 17
HbA1c, %	5.4 ą 0.7
FBS, mg/dL	98 ą 21
Total cholesterol, mg/dL	211 ą 35
Triglyceride, mg/dL	125 ą 89
HDL-C, mg/dL	61 ą 15
LDL-C, mg/dL	125 ą 30
Proteinuria, n (%)	31,498 (6%)
CKD, n (%)	98,816 (18%)
Medications
Anti-hypertensive drug, n (%)	159,140 (30%)
Anti-diabetic drug, n (%)	29,307 (5%)
Anti-dyslipidemia drug, n (%)	79,149 (15%)

Table 1:Baseline characteristic of all subjects.

Data are expressed as mean ą SD, number (percentage). BMI, body mass index; BP, blood pressure; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; FBS, fasting blood sugar; HbA1c, glycosylated hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.

Variables	Low Suita score n = 448,223	High Suita score n = 86,181	P value
Age, years	62 ą 9	69 ą 4	<0.0001
Male, n (%)	154,752 (29%)	75175 (87%)	<0.0001
Framingham risk score	6.0 ą 3.6	9.9 ą 2.4	<0.0001
BMI, kg/m2	23.2 ą 3.5	24.5 ą 3.2	<0.0001
Waist circumference, cm	84 ą 10	88 ą 8	<0.0001
Hypertension, n (%)	166,153 (37%)	64,973 (75%)	<0.0001
Systolic BP, mmHg	127 ą 17	139 ą 18	<0.0001
Diastolic BP, mmHg	76 ą 11	80 ą 11	<0.0001
Dyslipidemia, n (%)	237,225 (53%)	61,721 (72%)	<0.0001
Diabetes mellitus, n (%)	33,075 (7.4%)	29,114 (34%)	<0.0001
Smoking, n (%)	56,385 (13%)	26,006 (30%)	<0.0001
Biochemical data
eGFR, ml/min/1.73m2	77 ą 17	68 ą 18	<0.0001
HbA1c, %	5.3 ą 0.6	5.8 ą 1.0	<0.0001
FBS, mg/dL	96 ą 18	110 ą 31	<0.0001
Total cholesterol, mg/dL	211 ą 36	216 ą 37	<0.0001
Triglyceride, mg/dL	121 ą 89	148 ą 94	<0.0001
HDL-C, mg/dL	63 ą 16	53 ą 14	<0.0001
LDL-C, mg/dL	123 ą 31	134 ą 32	<0.0001
Proteinuria, n (%)	20,381 (4.6%)	11,117 (13%)	<0.0001
CKD, n (%)	64,008 (14%)	34,808 (40%)	<0.0001
Medications
Anti-hypertensive drug, n (%)	113,247 (25%)	45,893 (53%)	<0.0001
Anti-diabetic drug, n (%)	15,425 (3.4%)	13,882 (16%)	<0.0001
Anti-dyslipidemia drug, n (%)	65,270 (15%)	13,879 (16%)	<0.0001

	*Univariate analysis*
Variables	HR	95%CI	P value
*Aortic aneurysm rupture deaths*
Suita score*	4.605	3.281-6.466	<0.0001
Framingham risk score*	1.926	1.496-2.481	<0.0001
Waist circumference	1.046	1.016-1.077	0.0021
Alcohol consumption	2.094	1.093-4.011	0.0220
*Aortic dissection deaths*
Suita score*	1.989	1.558-2.539	<0.0001
Framingham risk score*	1.278	1.068-1.527	0.0067
Waist circumference	1.037	1.014-1.058	0.0009
Alcohol consumption	1.067	0.680-1.674	0.7760

	*Multivariate analysis*
Variables	HR	95%CI	P value
*Aortic aneurysm rupture deaths*
Suita score*	4.342	3.014-6.257	<0.0001
Suita score*	3.792#	2.564-5.609	<0.0001
Framingham risk score*	1.922	1.450-2.547	<0.0001
Framingham risk score*	1.823#	1.367-2.431	<0.0001
*Aortic dissection deaths*
Suita score*	1.992	1.524-2.602	<0.0001
Suita score*	1.705#	1.289-2.255	0.0002
Framingham risk score*	1.228	1.006-1.498	0.0433
Framingham risk score*	1.164#	0.950-1.427	0.1416

Tables at a glance

Figures at a glance