“M” represents Markhov process with 13 health states that are identical for each of the treatment options and a cycle length of three-month. Patients remain in the NVAF state until an event occurs. The transition probabilities of the events depend on the treatment. The branches from the state “NVAF” illustrate the possible events. The structure is similar for each treatment.
ASA = acetyl salicylic acid; CRNMB = clinically relevant non major bleed; ICH = intracranial hemorrhages; IS = ischemic stroke; MI = myocardial infarction; NVAF = non-valvular atrial fibrillation; Other M. Bleed = major bleed; SE = systemic embolism
Figure 1: Schematic representation of the Markhov model
Tables at a glance
Figures at a glance