Figure 1: Clinical trial flowchart
Placebo |
Collagen beverage |
|||
Subject number |
30 |
30 |
||
Female |
25 |
26 |
||
Male |
5 |
4 |
||
Age (years) |
38.8 |
37.7 |
||
Week 0 |
Week 8 |
Week 0 |
Week 8 |
|
AST (IU/L) |
18.1 ± 1.3 |
20.1 ± 2.0 |
16.2 ± 0.8 |
16.2 ± 1.0 |
ALT (IU/L) |
16.7 ± 1.9 |
17.6 ± 2.0 |
14.7 ± 1.8 |
15.5 ± 1.5 |
BUN (mg/dL) |
13.9 ± 0.6 |
12.3± 0.5 |
11.7 ± 0.5 |
10.9 ± 0.4 |
Creatinine (mg/dL) |
0.76 ± 0.03 |
0.77 ± 0.02 |
0.67 ± 0.02 |
0.68 ± 0.03 |
Data were expressed as the mean ±S.E.M; AST, aspartate aminotransferase; ALT, alanine aminotransferase; BUN, blood urea nitrogen. Significant difference versus baseline: **, p < 0.01
Table 1 : Demographic and results of biochemical analyses.
Figure 1: Clinical trial flowchart
Figure 2: The collagen beverage had anti-oxidation effect. The (A) total antioxidant capacity, (B) Glutathione S-transferase, (n = 30; mean value ± SD.) *, compared with baseline (week 0). #, compared with placebo) (***, p < 0.001, ###, p < 0.001)
Figure 3: The collagen beverage improved skin collagen, texture, elasticity, hydration. The (A) collagen, (B) texture, (C) elasticity, (D) hydration (n = 30; mean value ± SD.) *, compared with baseline (week 0) (*, p < 0.05, **, p < 0.01, ***, p < 0.001)
Figure 4: The collagen beverage improved skin lightness, melanin. The (A) lightness, (B) melanin, (C) image of skin pigmentation and skin tone (n = 30; mean value ± SD.) *, compared with baseline (week 0) (*, p < 0.05, **, p < 0.01, ***, p < 0.001)
Figure 5: The collagen beverage improved skin condition. 60 subjects were recruited and divided into 2 groups, one was the placebo group (n=30) and the other was the collagen beverage group (n=30). Take one bottle of beverage daily for 8 weeks, and then examined (A) skin sagging, roughness condition, (B) severity of sensitive skin, dry itchy skin and dry scaly skin, (C) severity of uneven skin tone, dull skin and yellowish skin tone. *, compared with baseline (week 0) (*, p < 0.05, **, p < 0.01, ***, p < 0.001)
Tables at a glance
Figures at a glance