NF1(N=75)

Controls(N=75)

Difference

NF1-Control (N=75)*

P-value

Socio-cultural characteristics and general cognitive level

Parents' highest socio-professional category - n (%)

 

 

 

0.1102

  Artisan, shopkeeper, company head, executive or intellectual job

34 (45.3%)

24 (32.0%)

 

 

  Others

41 (54.7%)

51 (68.0%)

 

 

Parents' education highest level - n (%)

 

 

 

0.0103

  Below 12 yo

23 (31.1%)

10 (13.3%)

 

 

  12 yo

19 (25.7%)

10 (13.3%)

 

 

  Above 12 yo

32 (43.2%)

55 (73.3%)

 

 

Total IQ: mean (SD)

89.2 (12.03)

98.4 (15.06)

-9.2 (17.16)

<.0001

Attentional capacity

Attention problems (CBCL):

Z-score - mean (SD)

 

1.8 (1.58)

 

1.2 (1.66)

 

0.6 (2.37)

 

0.0421

Omissions (CPT-II):

Percentile score -mean(SD)

 

59.5 (24.98)

 

59.4 (25.55)

 

-1.0 (31.82)

 

0.7920

Commissions (CPT-II):

Percentile score -mean(SD)

 

54.6 (26.71)

 

59.4 (25.55)

 

-5.6 (32.98)

 

0.1624

Hit RT Std. Error (CPT-II):

Percentile score - mean (SD)

 

62.3 (28.37)

 

64.7 (25.64)

 

-3.8 (35.28)

 

0.3781

Reading skills

Text reading comprehension (Lobrot):

 

 

 

 

Score - mean(SD)

72.3 (15.45)

69.1 (17.87)

2.3 (16.05)

0.2301

Sentences reading comprehension (Lobrot): Score - mean(SD)

21.5 (7.68)

20.7 (8.97)

0.4 (6.95)

0.6385

Reading accuracy (Alouette):

 

 

 

 

Z-score - mean (SD)

-1.6 (2.18)

-0.8 (1.49)

-0.7 (2.06)

0.0030

  Disabilities (≤-1.5SD) - n (%)

27 (36.0%)

18 (24.0%)

 

0.0636

Reading speed (Alouette):

 

 

 

 

Z-score - mean (SD)

-0.6 (0.94)

-0.6 (1.03)

-0.0 (0.35)

ND

  Disabilities (≤-1.5SD) - n (%)

14 (18.7%)

19 (25.3%)

 

0.1250

EVIP:

 

 

 

0.1083

Normalized score – mean(SD)

113.0 (14.66)

116.2 (14.08)

-3.2 (17.19)

 

Table 1Population socio-cultural characteristics, cognitive, attention and reading abilities

SD: Standard Deviation; n: number; ND: test not done as reading speed z-score was a matching criterion *CBCL was assessed for 73 pairs, CPT-II for 69 pairs and Lobrot test for 73 pairs

 

« Attention problem »z-scores (CBCL)

CPT-II

NF1

(N=71)

Controls

(N=71)

Omissions percentile–ρ(p-value)

0.09 (0.4319)

0.20 (0.0865)

Commissions percentile–ρ(p-value)

-0.10 (0.4020)

0.01 (0.9133)

Hit RT Std. Error percentile –ρ(p-value)

0.13 (0.2859)

0.12 (0.3069)

Perseverations percentiles–ρ p-value)

0.12 (0.3029)

0.21 (0.0777)

Table 2 Spearman correlations between « attention problem » z-scores of CBCL and CPT-II percentiles scores

ρ:correlation coefficient