Scheme 1: Synthesis of poly(L-cys)/rGO-AgNPs/GCE and the electrochemical determination of metronidazole
Electrochemical sensors |
Electrochemical methods |
Linear ranges (μmol L-1) |
Limit of detection (nmol |
Reference |
CuCo2O4/N-CNTs/MIP/GCE |
DPV |
0.005-0.1, 0.1-100 |
0.48 |
[8] Wang et al, 2019 |
NiMnO@pr-GO/GCE |
DPV |
0.1-234 |
0.09 |
[11] Vivekanandan et al. 2020 |
NSP-PC/GCE |
LSV |
0.1-45, 50-350 |
13 |
[12] Yalikun et al., 2019 |
CS-PC BPE/GCE |
DPV |
0.01-465 |
9 |
[13] Ranganathan et al. 2019 |
PrV/SCN/GCE |
Amperometry |
0.001-2444 |
0.8 |
[14] Kokulnathan and Chen 2019 |
ZIF-67C@rGO/GCE |
DPV |
0.5-1000 |
50 |
[15] Chen et al. 2019 |
O-gCN/GCE |
DPV |
0.01-2060 |
5 |
[36] Kesavan et al. 2021 |
C60-rGO-NF/SPE |
SWV |
0.5-34.0 |
35 |
[37] Materón et al. 2021 |
poly(L-Cys)/rGO-AgNPs/GCE |
DPV |
0.012-460 |
2.3 |
This work |
Table 1: Comparison of the present method and other reported electrochemical methods for determination of metronidazole in recent three years
Spiked (μg L-1) |
Found (μg L-1) |
Recovery (%) |
RSD (%) |
50 |
44.2 |
88.4 |
4.8 |
100 |
94.5 |
94.5 |
5.1 |
1000 |
106.8 |
106.8 |
3.4 |
Table 2: Recovery of the determination of MNZ in milk samples (n=5)
Tables at a glance
Figures at a glance