Characteristics

NCGC
(n= 4912)

CGC
(n= 2366)

P

Sex

<0.001

Female

2217 (45.1%)

492 (20.8%)

Male

2695 (54.9%)

1874 (79.2%)

Age (y)

<0.001

<60

1589 (32.3%)

970 (41.0%)

61-74

1806 (36.8%)

972 (41.1%)

>75

1517 (30.9%)

424 (17.9%)

Marital status

<0.001

Married

2972 (60.5%)

1679 (71.0%)

Unmarried *

1809 (36.8%)

641 (27.1%)

Unknown

131 (2.7%)

46 (1.9%)

Race

<0.001

White

2751 (56.0%)

2086 (88.2%)

African-American

761 (15.5%)

94 (4.0%)

Other

1400 (28.5%)

186 (7.9%)

Year of diagnosis

0.241

2004-2006

2066 (42.1%)

949 (40.1%)

2007-2008

1417 (28.8%)

719 (30.4%)

2009-2010

1429 (29.1%)

698 (29.5%)

Grade

<0.001

Well/moderate

1343 (27.3%)

869 (36.7%)

Poor/undifferentiated

3390 (69.0%)

1381 (58.4%)

Unknown

179 (3.6%)

116 (4.9%)

Surgery

<0.001

Gastrectomy          (partial,        subtotal,

3093 (63.0%)

360 (15.2%)

hemi-)

Near-total or total gastrectomy

737 (15.0%)

199 (8.4%)

Gastrectomy with the removal of a

534 (10.9%)

1493 (63.1%)

portion of the esophagus

Gastrectomy            with          en        bloc

538 (11.0%)

286 (12.1%)

resection of other organs

Gastrectomy or surgery

10 (0.2%)

28 (1.2%)

T stage

<0.001

T1

1125 (22.9%)

481 (20.3%)

T2

620 (12.6%)

262 (11.1%)

T3

1706 (34.7%)

942 (39.8%)

T4a

1087 (22.1%)

549 (23.2%)

T4b

374 (7.6%)

132 (5.6%)

N stage

<0.001

N0

1991 (40.5%)

797 (33.7%)

N1

1765 (35.9%)

1139 (48.1%)

N2

860 (17.5%)

321 (13.6%)

N3

296 (6.0%)

109 (4.6%)

Stage

<0.001

IA/IB

1443 (29.4%)

587 (24.8%)

IIA/IIB

1693 (34.5%)

969 (41.0%)

IIIA/IIIB/IIIC

1776 (36.2%)

810 (34.2%)

  Characteristics           n

5-year CSS

P

HR

95% CI

P

Sex

0.985

NI

Male

4569

45%

Female

2709

46%

Age (years)

<0.001

<60

2559

51%

Reference

61-74

2778

47%

1.372

1.7271-1.481

<0.001

>75

1941

34%

2.227

2.053-2.415

<0.001

Marital status

<0.001

Married

4651

48%

Reference

Unmarried*

2450

40%

1.158

1.082-1.238

<0.001

Unknown

177

49%

0.983

0.794-1.216

0.837

Race

<0.001

White

4837

42%

Reference

African-American

855

44%

1.026

0.928-1.135

0.618

Other

1586

56%

0.755

0.693-0.823

<0.001

Year of diagnosis

<0.001

2004-2006

3015

41%

Reference

2007-2008

2136

45%

0.922

0.856-0.992

0.030

2009-2010

2127

53%

0.773

0.714-0.837

<0.001

Tumor location

<0.001

Non-cardia

4912

48%

Reference

Cardia

2366

39%

1.303

1.216-1.397

<0.001

Grade

<0.001

Well/moderate

2212

55%

Reference

Poor/undifferentiated

4771

40%

1.328

1.234-1.430

<0.001

Unknown

295

58%

1.058

0.879-1.275

0.550

Surgery

<0.001

Gastrectomy (partial, subtotal, hemi-)

3453

50%

Reference

Near-total or total gastrectomy

936

44%

1.012

0.642-1.595

0.960

Gastrectomy with the removal of a portion of the esophagus

2027

40%

1.208

0.762-1.914

0.421

Gastrectomy WITH en bloc

resection

of

other

824

40%

1.183

0.752-1.863

0.467

organs

Gastrectomy or surgery

38

49%

1.170

0.738-1.854

0.504

Lymph nodes examined#

0.987

0.984-0.990

<0.001

T stage

<0.001

NI

T1

1606

79%

T2

882

63%

T3

2648

36%

T4a

1636

24%

T4b

506

20%

N stage

<0.001

NI

N0

2788

70%

N1

2904

37%

N2

1181

19%

N3

405

9%

Stage

<0.001

IA/IB

2030

79%

Reference

IIA/IIB

2662

44%

3.131

2.813-3.485

<0.001

IIIA/IIIB/IIIC

2586

20%

6.476

5.826-7.197

<0.001