Figure 1: Endoscopic aspect of a budding process of the left FN. (Iconography of the service)
case |
age |
Gender |
Presenting symptoms |
TNM classification |
treatment |
Evolution (5-year follow-up) |
1 |
51 |
M |
-nasal obstruction. |
T4N1M0 |
Palliative chemotherapy. (cyclophosphamide-vincristine) |
Died after the 2nd cure of |
2 |
65 |
F |
-Nasal obstruction. |
T2N0M0 |
Tumor resection by endoscopic endonasal approach (EEA), |
Complete |
3 |
50 |
M |
-Nasal obstruction. |
T3N0M0 |
Tumor resection by EEA followed by radiotherapy. |
Complete remission. |
4 |
63 |
M |
-nasal obstruction. |
T4N1M1 |
Palliative chemotherapy. |
Died 2 months after starting treatment. |
5 |
35 |
F |
-nasal obstruction. |
T3N0M0 |
Surgical resection by Paralateral nasal pathway + external radiotherapy. |
Good clinical evolution |
6 |
40 |
F |
-nasal obstruction. |
T2N0M0 |
Surgical resection by EEA |
Good clinical evolution |
7 |
26 |
f |
-nasal obstruction. |
T3N0M0 |
Surgical resection by EEA followed by radiotherapy. |
Good clinical evolution |
8 |
40 |
H |
-nasal obstruction. |
T4N0M0 |
Combined tumor resection followed by complementary radiotherapy (60 Gy) |
Good evolution on a current follow-up of 2 years. |
9 |
60 |
f |
-Nasal obstruction. |
T1N0M0 |
Surgical resection by EEA |
Complete remission |
10 |
70 |
H |
-Nasal obstruction. |
T3N0M0 |
Combined tumor resection followed by complementary radiotherapy |
No recurrence on a follow-up of 18-month. |
11 |
40 |
f |
-Nasal obstruction. |
T1N0M0 |
Surgical resection by EEA |
Complete remission |
12 |
54 |
f |
-Nasal obstruction. |
T3N0M0 |
Combined tumor resection followed by complementary radiotherapy |
Complete |
Authors |
Number of cases / Number of years |
Age/ extremes of ages |
Sex ratio (H/F) |
NAKAGAWA [5] |
22 cases over 8 years |
49 years (27-83) |
10/12 |
GAYE [6] |
12 cases over 7 years |
20 years (11-66) |
7/5 |
LAPIERRE [7] |
10 cases over 12 years |
56 years (32-83) |
7/3 |
CHAHED [8] |
3 cases over 10 years |
54 years (23-85) |
1/2 |
KERMANI [9] |
7 cases over 26 years |
36 years (11-63) |
2/5 |
Our study |
12 cases over 15 years |
48 years (26-70) |
5/7 |
Table 1: The Hyams histological grading system: HW rosettes, FW rosettes [30}
Figure 1: Endoscopic aspect of a budding process of the left FN. (Iconography of the service)
Figure 2: axial facial CT showing left naso-ethmoidal heterogeneous process and tissue density with endocranial extension and towards the homolateral orbit. (Iconography of the service)
Figure 3: MRI T1 with gadolinium: large mass located in nasal fossas. Spreading to the left maxilla sinus invading the left orbit. Spreading to the anterior portion of skull base. Involvement Affectation of inferior orbital fissure and right cavernous sinus. [23]
Figure 4: MRI T1 with gadolinium: Intrasinusal solid mass (left side) with extensionspreading to anterior cerebral fossa. [23]
Figure 5: General appearance of the tumor. The cells are arranged according to a lobular pattern, separated by loose fibrovascular fibers. Necroses are visible in same central lobules (arrows) [29]
Figure 6: coronal section of MRI. (a) pre-operative, (b) One year after treatment (Iconography of ENT department)
Tables at a glance
Figures at a glance