Figure 1: Extraction yield for the different samples.
Sm: Solanum marcrocarpon; To: Telfairia occidentalis
Metabolites/extracts |
Sm |
To |
Flavonoid |
+ + + |
++ |
Total phenols |
+ + + |
+ ++ |
Coumarin |
+ + + |
+ + + |
Anthocyanin |
- |
- |
Saponin |
+ |
+ + + |
Tannins |
+ + + |
+ + + |
Table 1: Summary of phytochemical screening
Sm: Extract of Solanum marcrocarpon; To: Extract of Telfairia occidentalis;
- = absence; +: low presence; ++: Moderate presence; +++: abundant presence 3- Toxicity study
Test/lot |
TN |
Sm |
To |
ASAT |
|
|
|
ALAT |
|
|
|
Urea |
|
|
|
Creatinin |
|
|
|
Protein |
|
|
|
Table 2: Summary of biochemical parameters after the toxicity study
TN: rat having received no extract; Sm: rat treated with Solanum marcrocarpon extract; To: rat treated with Telfairia occidentalis extract.
Each value represents the mean ± Standard deviation, the number of rats per batch (N) = 4.
Parameter / lots |
TN |
TP |
Sm |
To |
Ref |
ASAT |
26.46±1,62a |
55,65± 0,94c |
29,70±0,86b |
40,76±1 ,01b |
35,97±1,18a |
ALAT |
37.01±1,93a’b’ |
61,62±2,91c’ |
39,80±2,33b’ |
39,14±2,51b’ |
34,94±2,63a’ |
UREE |
0,17±0,007a |
0,26±0,007b |
0,15±0,008c |
0,142±0,007c |
0,17±0,008asup> |
Créatinin |
0,50±0,03ab |
0,59±0,02 b |
0,43±0,01ab |
0,47±0,01ab |
0,43±0,01a |
Protein |
118,22±1.57e |
80,88±1.01a |
109,74±3.34d |
90,65±2,89b |
104,98±2,64c |
TG |
0,89±0,008ab |
1,07±0,007a |
0,93±0,005b |
0,93±0,007ab |
0,88±0,005b |
HDL-C |
0,58±0,008d |
0,47±0,005a |
0,56±0,008c |
0,54±0,006d |
0,53±0,003b |
LDL-C |
0,12±0,008a |
0,34±0,004d |
0,18±0,009c |
0,20±0,013c |
0,15±0,018b |
CT |
0,91±0,003b |
1,01±0,006e |
0,95±0,007d |
0,94±0,006cd |
0,89±0,006a |
Glucose |
0,79±0.011a |
0,99±0,018b |
0,81±0,013a |
0,80±0,019a |
0,791±0,012a |
Leptin |
5,99± 0,27a |
3,470±0,44b |
5,99±0,23a |
5,55±0,44a |
5,60±0,32a |
Table 3: Summary of biochemical results
TN: rats that did not receive any extract; TP: rats having received no extras but co-consuming a diet enriched in fat and sugar; Sm: rats treated with Solanum marcrocarpon extract; To: rats treated with Telfairia occidentalis extract; Ref: rats receiving the reference drug
Figure 1: Extraction yield for the different samples.
Sm: Solanum marcrocarpon; To: Telfairia occidentalis
Figure 2: Evolution of the food intake of rats as a function of time
Figure 3: Evolution of the body weight of rats as a function of time
Tables at a glance
Figures at a glance