Figure 1 Figure 1: Scatter plots with least square fit for the disease group
Figure 1a: Scatter plot showing a positive correlation between PBAC and left eye PSD (p=0.009)
Figure 1b: Scatter plot showing a negative correlation between PBAC and left eye MD (p=0.003)
Figure 1c: Scatter plot showing negative correlation between PBAC and left eye VFI (p=0.010)
Figure 1d: Scatter plot showing a negative correlation between PBAC and left eye average NFL thickness (p=0.11)
Figure 2 Figure 2 Scatter plots with least square fit for all subjects
Figure 2a: Scatter plot showing a positive correlation between PBAC and left eye PSD (p<0.0001)
Figure 2b: Scatter plot showing a negative correlation between PBAC and left eye MD (p=0.002)
Figure 2c: Scatter plot showing negative correlation between PBAC and left eye VFI (p=0.003)
Figure 2d: Scatter plot showing a negative correlation between PBAC and left eye average NFL thickness (p=0.266)
|
Disease group |
Control group (n=23) |
p value |
Mean age |
45 +/- 7 |
48 +/- 6 |
0.1 |
Family history of glaucoma |
2 |
4 |
0.33# |
Gonioscopy |
Open |
Open |
|
Spherical equivalent (dioptre) |
-1.7 +/- 1.7 |
-1.9 +/- 2.7 |
0.8 |
Central corneal thickness (um) |
548 +/- 26 |
548 +/- 26 |
0.9 |
IOP (mmHg) |
15 +/- 3 |
14 +/- 2 |
0.4 |
CDR |
0.3 |
0.3 |
1.0 |
PBAC |
1815 +/- 1944 |
35.3 +/- 49.6 |
<0.0001 |
Menorrhagia duration (years) |
2.6 |
NA |
|
Ferritin (ng/mL) |
44.05 +/- 48.3 (n=23) |
NA |
|
Pre-transfusion Hb (g/dl) |
8.04 +/- 1.97 (n=23) |
NA |
|
Table1 Table showing baseline data for study subjects
|
Disease group (n=25) |
Control group |
p value |
PSD |
2.73 +/- 1.9 |
1.82 +/- 0.42 |
<0.01 |
MD |
-3.0 +/- 3.3 |
-2.28 +/- 1.26 |
0.35 |
VFI |
95.64 +/- 7.5 |
97.4 +/- 1.9 |
0.34 |
NFL |
105.6 +/- 11.4 |
103.8 +/- 10.0 |
0.57 |
Table2 Table comparing the mean visual field global indices and average NFL thickness in the disease group and control group
|
All subjects |
Disease group |
Control group (n= 23) |
|
PSD against PBAC |
0.63 |
0.60 |
-0.28 |
|
MD against PBAC |
-0.61 |
-0.68 |
0.46 |
|
VFI against PBAC |
-0.61 |
-0.65 |
0.22 |
|
NFL against PBAC |
-0.17 |
-0.33 |
0.02 |
Table3 Table tabulating the correlation coefficient calculated using Pearson’s correlation analysis
|
Normal menses (n=9) |
Menopause |
p value |
PSD |
1.66 +/- 0.44 |
1.95 +/- 0.38 |
0.15 |
MD |
-1.66 +/- 1.33 |
-2.79 +/- 0.97 |
0.06 |
VFI |
97.8 +/- 1.8 |
97.1 +/- 2.0 |
0.45 |
NFL |
104.8 +/- 10.5 |
103.2 +/- 10.1 |
0.72 |
Table4 Table comparing the mean VF indices and NFL thickness between subjects with normal menses and subjects with menopause
|
All subjects |
Control group |
PSD against PBAC |
0.63 (<0.003) |
0.09 (0.83) |
MD against PBAC |
-0.67 (0.001) |
0.14 (0.72) |
VFI against PBAC |
-0.64 (0.003) |
0.21 (0.59) |
NFL against PBAC |
-0.25 (0.16) |
-0.2 (0.6) |
Table5 Table tabulating the correlation coefficient calculated using Pearson’s correlation analysis, with menopause subjects excluded