Figure 1: showing the toxic effects of Paraben on AST, ALT and Bilirubin with the ameliorative effects of mushroom in comparison to control group. Mean ± SE (P < 0.05)

Figure 2: showing the toxic effects of Paraben on total protein, globulin and albumin with the ameliorative effects of mushroom in comparison to control group. Mean ± SE (P < 0.05)

Figure 3: showing the toxic effects of Paraben on serum creatinine and urea with the ameliorative effects of mushroom extracts in comparison to control group. Mean ± SE (P < 0.05)

Figure 4: Histopathological figure of the livers treated with butylparaben and others treated with butylparaben and mushroom. Livers are showing severe vascular congestion (thick arrow) (A& B & C & D) and mild vascular congestion (thick arrow) (F), prominent vacuolar degeneration (arrowhead) (A & D) and mild degenerative changes (arrowhead) (F & G), notable local inflammatory reaction (asterisk) (D) and mild inflammation (asterisk) (H), periportal edema (lightning Bolt) (C), necrotic vascular lining (U-turn arrow) (D), mild dilated hepatic sinusoids (double line arrow) (E & H), high mitotic frequency (thin arrow) (D) and low mitotic frequency (thin arrow) (E). (A&B&C&D: livers treated with butylparaben; E&F&G&H: livers treated with butylparaben and mushroom). H& E: A: X50, B&C&D&E&F&G&H: X100 respectively

Figure 5: Histopathological figure of the kidneys treated with butylparaben and others treated with butylparaben and mushroom. Kidneys are showing severe vascular congestion (asterisk) (A&C&D) and mild congestion (asterisk) (H), apparent leukocytic infiltration (oval) (A&D) and mild inflammatory reaction (H), complete tubular epithelium necrosis (thick arrow) (B) and restoration of a tubular structure (triangle & thick arrow) (E&F), congestion of glomerular capillaries (thin arrow) (C), necrotic glomeruli with mesangial cell proliferation (Lightning Bolt) (D) and mild mesangial proliferation (Lightning Bolt) (G), and wide tubular lumen (double line arrow) (F&G). (A&B&C&D: kidneys treated with butylparaben; E&F&G&H: kidneys treated with butylparaben and mushroom). H& E: A&E: X50, B&C&D&F&G&H: X100 respectively