Figure 1: The effect of AL + RP, Artefan AL + Bp and Artefan+ placebo treatment groups on parasite clearance. Effect of AL + placebo on parasitemia (a). effect of AL +BP (b) and the effect of AL +RP (c) on parasitemia of children infected with Plasmodium falciparum. asterisks represent statistical difference between the different treatment days (D0,D1,D2, and D7)

Figure 2: Effects of RP +AL BP *AL and Placebo + AL on the parasite clearance rate and a comparison between BP+AL vs Placebo +AL (a),and RP AL vs Placelxbo on the parasite clearance rate of plasmcxiium falciparum infected children. Asterisks represents statistical difference between treatment days (DO, 01, 02 and 07) as well as between the different treatment groups (BP+AL RP+AL and AL+ Placebo)and also comparison vs placebo 4 AL and RP •AL vs Placebo + AL treatment groups While nS means not statistically Signifi-

Figure 3: comparison of the effects of RP and BP (bl ) on the Hb level of the control group and also comparison of the effects of AL + Placebo, RP and BP on the Hb level of Test and Control groups. Asterisks represents statistical difference between control groups (RP and BP) as well as between the test group (Placebo + AL), while the letters represent differences between control groups and test group

Figure 4: Effect of Telfairia occidentalis on the liver activity of non-infected children (Fig 4a and 4b) and children infected with Plasmcxlium falciparum (figure 4c). Asterisks represents statistical difference between the different treatment days (DO, Dl, D2 and D7) while ns represents not statistically significant

Figure 5: comparison of BP and RP + AL effect on AST (fig 5a), ALT (fig 5b) and GGT (fig 5c) of Plasmodium falciparum infected children, Asterisks represents comparison between the two treatment groups (BP + AL and RP + AL) on the different days Of treatment, nS represents statistically not significant while the letters represent the different treatment groups

Figure 6: comparison Of the effect between BP AL and AL + Placebo on the AST (6a), ALT (6b) and GGT(6c) enzymes Of Plasmodium falciparum infected children, Asterisks represents difference between AST, ALT and GGT levels during the different treatment days in BP + AL compared AL *Place-IN' treatment groups. i-Vhereas a and b represent the difference in the serum levels of ALT, AST and GGTbetween BP+ ALtreatment group compared to AL + Placelk" treatment group

Figure 7: comparison of the effect between RP + AL and AL + Placebo on the liver enzymes activity, AST (a), ALT(b) and GGT(c) serum level of malaria positive children. Asterisks represents statistical difference between treatment rou s (RP + AL and AL + Placebo) and also comparison between RP + AL treatment and AL Placebo treatment groups. The letters represent the difference in serum levels between the RP 4 AL treatment group and AL Placebo treatment group

Figure 8: comparison of Parasitemia between AL + placebo vs. AL RP. AL placebo Vs. AL BP and AL + RP Vs. AL + BP treatment groups. Asterisks represents comparison the three treatment groups (AL 4 placebo. AL + RP. AL + BP) among subjects Of the different groups. ns represents statistically not significant while the letters represent the different treatment groups

Figure 9: comparison Of HB levels Ektween AL + placebo vs. AL + RP. AL vs. AL + BP and AL 4 RP vs. AL + BP treatment groups.Asterisks represents comparison between the three treatment groups (AL + placebo, AL + RP, AL + BP) among subjects of the different groups. ns represents statistically not significant

Figure 10: comparison of liver enzyme activity levels AL + placebo vs. AL + RP, AL placebo Vs. AL + BP and AL RP vs- AL BP treatment groups. Asterisks comparison the three treatment groups (AL + placebo, AL + RP. AL + BP) among subjects of the different groups, ns represents statistically not significant