Figure 1: Whole framework based on network pharmacology
FIGURE 2
Figure 2: Active Ingredients of EZP: orange represents LLF, pink represents EH, and red represents the same active ingredients
FIGURE 3
Figure 3: POI gene prediction analysis
FIGURE 4
Figure 4: the common targets of EZP and POI
FIGURE 5
Figure 5: Drug active ingredients and disease target network
FIGURE 6
Figure 6: Protein-Protein interaction network
FIGURE 7
Figure 7: Process of topological screening for the PPI network
FIGURE 8
Figure 8: GO enrichment of EZP active components in the treatment of common targets of POI
FIGURE 9
Figure 9: Enriched KEGG pathways of potential targets for treating POI from the main active ingredients of EZP
FIGURE 10
Figure 10: Molecular docking of compounds with core targets. (a) Docking process of quercetin with AKT1; (b) Docking process of quercetin with TP53; (c) Docking process of quercetin with MAPK1; (d) Docking process of quercetin with TNF; (e) Docking process of quercetin with JUN; (f) Docking process of quercetin with RB1; (g) Docking process of quercetin with MYC
Figures at a glance