Figure 1: Flow diagram of the study, schematizing the women progress
Variables |
Total Sample (N=86) |
Mean age in years ± SD |
35 ± 8 |
Age group |
n (%) |
18-29 |
21 (24.4) |
30-39 |
37 (43.0) |
40-49 |
28 (32.6) |
Highest level of education |
n (%) |
Elementary School |
0 |
Middle School |
12 (14.0) |
Secondary School |
20 (23.3) |
Bachelor |
6 (7.0) |
Master’s Degree |
37 (43.0) |
Doctoral Degree |
9 (10.5) |
Civil Status |
n (%) |
Single |
31 (36.0) |
Married or Common-Law Marriage |
49 (57.0) |
Divorced |
6 (7.0) |
Widowed |
0 |
Occupation |
|
Studying |
9 (10.5) |
Working |
68 (79.1) |
Inactive |
9 (10.5) |
Timepoint of first diagnostic |
|
Less than a year |
33 (38.4) |
Between 1 to 5 years |
27 (31.4) |
More than 5 years |
26 (30.2) |
Method of diagnosis |
|
Surgical diagnosis |
23 (26.7) |
Clinical diagnosis only |
63 (73.3) |
Endometriosis classification+ |
|
Stage I |
14 (16.3) |
Stage II |
11 (12.8) |
Stage III |
13 (15.1) |
Stage IV |
29 (33.7) |
Not possible to classify |
19 (22.1) |
Symptoms experienced in the past 4 weeks |
|
Dysmenorrhea |
62 (72.1) |
Dysuria |
15 (17.4) |
Dyschezia |
24 (27.9) |
Dyspareunia |
49 (57.0) |
Chronic pelvic pain |
57 (66.3) |
Asthenia |
25 (29.1) |
Gastrointestinal alterations |
20 (23.3) |
Abnormal uterine bleeding |
29 (33.7) |
Previous treatment |
|
Surgical |
23 (26.7) |
Hormonal |
36 (41.9) |
Analgesic |
12 (14.0) |
Table 1 : Participant�s socio-demographic and clinic characteristics at baseline
EHP-30 Score |
|
||||||||
mean |
std |
median |
Range |
CI 95% |
|
||||
min |
max |
lower limit |
upper limit |
p-value |
|||||
Pain |
Baseline |
60.2 |
18.4 |
61.8 |
20 |
89.1 |
51.6 |
62.9 |
<0.001 |
3M |
40.6 |
20.4 |
34.5 |
20 |
94.5 |
31.5 |
42.2 |
||
6M |
33.4 |
17.7 |
23.6 |
20 |
78.2 |
28.3 |
38.8 |
||
Change from baseline at month 3 |
-19.1 |
25.0 |
-14.5 |
-74.5 |
23.6 |
-26.5 |
-14.2 |
|
|
Change from baseline at month 6 |
-22.6 |
23.4 |
-25.5 |
-60 |
25.5 |
-30.4 |
-17.0 |
|
|
Control and powerlessness |
Baseline |
64.0 |
23.3 |
66.7 |
20.0 |
100.0 |
55.6 |
68.2 |
<0.001 |
3M |
43.2 |
20.7 |
36.7 |
20.0 |
100.0 |
33.4 |
46.4 |
||
6M |
35.6 |
21.4 |
26.7 |
20.0 |
96.7 |
29.6 |
42.0 |
||
Change from baseline at month 3 |
-20.5 |
25.0 |
-18.4 |
-73.3 |
33.3 |
-28.9 |
-15.0 |
|
|
Change from baseline at month 6 |
-25.0 |
25.0 |
-26.7 |
-66.7 |
40.0 |
-33.2 |
-18.9 |
|
|
Emotional well-being |
Baseline |
59.1 |
18.8 |
60.0 |
20.0 |
96.7 |
50.0 |
62.2 |
<0.001 |
3M |
43.5 |
22.0 |
43.3 |
20.0 |
93.3 |
35.9 |
48.5 |
||
6M |
36.9 |
17.6 |
36.7 |
20.0 |
93.3 |
32.0 |
42.5 |
||
Change from baseline at month 3 |
-14.5 |
23.5 |
-13.3 |
-80.0 |
46.7 |
-20.4 |
-7.4 |
|
|
Change from baseline at month 6 |
-18.0 |
22.7 |
-20.0 |
-63.3 |
43.3 |
-25.5 |
-12.2 |
|
|
Social Support |
Baseline |
56.8 |
21.4 |
60 |
15 |
95.0 |
48.5 |
60.9 |
<0.001 |
3M |
45.1 |
24.1 |
45.0 |
20.0 |
100.0 |
35.6 |
49.1 |
||
6M |
37.7 |
21.1 |
30.0 |
20.0 |
100.0 |
31.7 |
44.3 |
||
Change from baseline at month 3 |
-12.0 |
26.2 |
-10.0 |
-70.0 |
55.0 |
-19.9 |
-4.6 |
|
|
Change from baseline at month 6 |
-15.9 |
26.0 |
-15.0 |
-70.0 |
50.0 |
-20.6 |
-4.7 |
|
|
Self-image |
Baseline |
54.6 |
23.9 |
30.0 |
20.0 |
100.0 |
43.5 |
58.2 |
0.015 |
3M |
41.9 |
24.0 |
33.3 |
20.0 |
100.0 |
32.2 |
44.9 |
||
6M |
38.7 |
20.0 |
33.3 |
20.0 |
100.0 |
32.3 |
44.2 |
||
Change from baseline at month 3 |
-12.3 |
23.1 |
-6.7 |
-66.7 |
53.3 |
-19.7 |
-5.0 |
|
|
Change from baseline at month 6 |
-11.1 |
28.5 |
-6.7 |
-60.0 |
60.0 |
-24.3 |
-9.0 |
|
Table 2 : EHP-30 modular scores and changes from baseline
|
From baseline to 3 months |
From baseline to 6 months |
||||
|
Improved |
Non-changed |
Deteriorated |
Improved |
Non-changed |
Deteriorated |
Pain |
48 (72.7) |
6 (9.1) |
12 (18.2) |
37 (78.7) |
3 (6.4) |
7 (14.9) |
Control and powerlessness |
48 (72.7) |
8 (12.1) |
10 (15.2) |
40 (85.1) |
2 (4.3) |
5 (10.6) |
Emotional well-being |
47 (71.2) |
3 (4.5) |
16 (24.2)) |
34 (72.3) |
6 (12.8) |
7 (14.6) |
Social Support |
42 (63.9) |
10 (15.2) |
14 (21.2) |
30 (63.8) |
9 (19.1) |
8 (17.0) |
Self-image |
39 (59.1) |
13 (19.7) |
14 (21.2) |
25 (53.2) |
11 (23.4) |
11 (23.4) |
Table 3 : Description of the improved, non-changed and deteriorated group at follow-up [n (%)]
Figure 1: Flow diagram of the study, schematizing the women progress
Figure 2: Changes in core EHP-30 scores from baseline to month 3 (3M) and to month 6 (6M) Results demonstrate proportions of patients with deterioration, no change and improvement defined as >0, 0 and < 0 difference in EHP-30 scores between baseline and questionnaires at month 3 and 6. Data were analyzed in 66 and 47 patients after 3- and 6-months follow-up, respectively. EHP-30, Endometriosis Health Profile-30 questionnaire
Tables at a glance
Figures at a glance