Figure 1 Kaplan Meier survival function by baseline ART regimen

 

Overall
(n= 100)

Intravaginal Misoprostol
(n=50)

Surgical Evacuation
(n=50)

 

Analysis

Age (years)

28.0 (25.0,32.8)

30.0 (25.8,34.0)

27.0
(25.0,32.0)

Z=-1.033
p=0.302

Ethnicity, n (%)

  • Malays
  • Chinese
  • Indians
  • Others

 

77 (77.0)
15 (15.0)
3 (3.0)
5 (5.0)

 

41 (82.0)
8 (16.0)
0 (0.0)
1 (2.0)

 

36 (72.0)
7 (14.0)
3 (6.0)
4 (8.0)

 

Χ2=5.191
p=0.158

Parity, n (%)

  • 0
  • ≥ 1

 

45 (31.0)
55(69.0)

 

22 (44.0)
28 (56.0)

 

23 (46.0)
27 (54.0)

 

Χ2=0.040
p=1.000

Gestational age (weeks ± IQR)

10.0 (8.4,11.6)

10.0      
(8.6, 11.5)

10.0 (8.3,11.7)

Z=-0.031
p=0.975

Hb pre-treatment (g/dl ± IQR )

12.3 (11.4,13.4)

12.4 (11.7,13.3)

12.1 (11.0,13.4)

Z=-1.249
p=0.212

Endometrial thickness (mm ± IQR)

23.5 (21.0,30.0)

24.0 (21.0,34.0)

22.5 (20.0,30.0)

Z=-1.096
p=0.273

Table1 Baseline characteristics

All parameter expressed in median (quartile) unless specified

 

Overall
(n= 100)

Intravaginal Misoprostol
(n= 50)

Surgical Evacuation
(n=50)

p-value

Successful evacuation,
n (%)

  • Yes
  • No

 

96 (96.0)
4 (4.0)

 

47 (94.0)
3 (6.0)

 

49 (98.0)
1 (2.0)

 

χ2=1.042
p=0.617

Table2 Study outcome

 

Frequency

Percentage

1 dose

13

26

2 doses

23

46

3 doses

14

28

Total

50

100

Table3 Requirement for misoprostol doses

 

Overall
n=100

Intravaginal Misoprostol
n=50

Surgical Evacuation
n=50

p-value

Duration of bleeding (days ± IQR)

7.0 (5.0,7.0)

6.0 (5.0,7.0)

7.0 (5.0,7.0)

Z=-0.688
p=0.491

Reduction of Hb day 1 (g/dl ± IQR)

0.4 (0.0,1.0)

0.2 (0.0,0.8)

0.7 (0.2,1.2)

Z=-2.431
p=0.015*

Reduction of Hb day 14
(g/dl ± IQR)

0.2 (0.0,0.8)

0.1 (0.0,0.7)

0.4 (0.0,0.8)

Z=-1.129
p=0.259

Table4 Other clinical outcome

*p < 0.05

All parameter expressed by median (quartile) unless specified

 

Overall
(n=100)

Intravaginal Misoprostol
(n=50)

Surgical Evacuation
(n=50)

p-value

Nausea, n (%)

3 (3)

3 (6)

0 (0)

χ2=3.093
p=0.242

Vomiting, n (%)

2 (2)

2 (4)

0 (0)

χ2=2.041
p=0.495

Diarrhoea, n (%)

10 (10)

10 (20)

0 (0)

χ2=11.111
p=0.001*

Fever, n (%)

 

11 (11)

11 (22)

0 (0)

χ2=12.360
p=0.001*

Table5 Side effects of both study groups within 24 hours

*p< 0.01