Figure 1 Options for BRCA carriers who plan to utilize PGD
This algorithm may be used to manage fertility preservation options for BRCA carriers who plan to use PGD to identify affected embryos and avoid transfer of BRCA mutation to offspring.
Figure 2 Options for BRCA carriers who do not plan to utilize PGD
This algorithm may be used to manage fertility preservation options for BRCA carriers who elect not to utilize PGD.
|
Lifetime Breast Cancer Risk |
Lifetime Ovarian Cancer Risk |
BRCA 1 |
57-72% |
40-59% |
BRCA 2 |
49-69% |
17-18% |
General Population |
12% |
1.4% |
Table1 Demographics for Survey Participants