Figure 1 Options for BRCA carriers who plan to utilize PGD

This algorithm may be used to manage fertility preservation options for BRCA carriers who plan to use PGD to identify affected embryos and avoid transfer of BRCA mutation to offspring.

Figure 2 Options for BRCA carriers who do not plan to utilize PGD

This algorithm may be used to manage fertility preservation options for BRCA carriers who elect not to utilize PGD.

 

Lifetime Breast Cancer Risk

Lifetime Ovarian Cancer Risk

BRCA 1

57-72%

40-59%

BRCA 2

49-69%

17-18%

General Population

12%

1.4%

Table1 Demographics for Survey Participants