
Figure 1: Flow chart for the study and the follow up
Figure 1: Flow chart for the study and the follow up
Figure 2: An excelchart of the patients with the result of the follow up samples. The molecular test are either neg = no BV, pos = BV and if candida are detected or missing sample. If the patient treated with dequalinium still is cured the background is yellow. The six patients cured at 12
months are shown in green. Relapse are shown in grey and lost to follow up in red.
The discordant results between the microscopy and the molecular tests are shown with red text
|
Molecular diagnostic test |
|
||
|
|
BV |
Normal |
|
Wet smear |
BV |
33 |
4 |
37 |
Normal |
6 |
73 |
79 |
|
|
|
39 |
77 |
116 |
Table 1: The kappa coefficient value was calculated as κ = 0.80 (0.69–0.92) considering the microscope slide analysis using the modified Hay/Ison classification compared with the molecular diagnostic test. The sensitivity was 0.85, the specificity was 0.95, the positive predictive value was 0.89, and the negative predictive value was 0.92.
|
Molecular diagnostic test |
|
||
|
|
BV |
Normal |
|
Wet smear |
BV |
35 |
3 |
38 |
Normal |
4 |
74 |
78 |
|
|
|
39 |
77 |
116 |
Table 2:After re-evaluation of the air-dried wet smears, the calculated kappa coefficient value increased to κ = 0.86 (0.76–0.96) considering the microscope slide analysis using the modified Hay/Ison classification compared with the molecular diagnostic test. The sensitivity was 0.90, the specificity was 0.96, the positive predictive value was 0.92 and the negative predictive value was 0.95.
Tables at a glance