score |
Clinical symptoms |
|
Clinical signs |
|||||
Vulvar itching |
Vulvar pain |
Dyspareunia |
Skin color |
Skin morphology |
score |
Affected area |
||
0 |
None |
None |
None |
Normal |
Normal |
0 |
Normal |
|
1~3分 |
Mild |
Mild |
Mild |
Mild |
Mild atrophy/thin |
1 |
One part of the clitoris/labia minora/ labia majora |
|
4~6分 |
Moderate |
Moderate |
Moderate |
Moderate |
Moderate atrophy/thin |
2 |
2 parts of Clitoris/labia minora/labia majora |
|
7~10分 |
severe |
Severe |
Severe |
Severe pale |
Severe atrophy/fragile |
3 |
Clitoris, labia minora, labia majora perineum and perianal |
Table 1 : VLS clinical symptoms and signs scoring criteria
|
|
Age (years) |
26~73(50.7±13.4) |
Post-menopausal |
33(60%) |
Duration of itching(years) |
0.5~20(7.19±5.65) |
Itching |
55(100%) |
History of Thyroid disorders |
20(36.4%) |
Diabetic |
1(2.5%) |
History of extragenital LS |
1(2.5%) |
Family history of VLS |
3(5.4%) |
History of IUD |
32(58.2%) |
History of oral contraceptive |
21(38.2%) |
|
|
Table 2 : Demographics
score |
Clinical symptoms n(%) |
|
Clinical signs n(%) |
|||||
Vulvar itching |
Vulvar pain |
Dyspareunia |
Skin changes |
Morphological changes |
score |
Vulvar area |
||
0 |
- |
8(14.5%) |
10(18.1%) |
1(1.8%) |
8(14.5%) |
0 |
6(10.9%) |
|
1~3 |
13(23.6%) |
20(36.4%) |
14(25.4%) |
7(12.7%) |
8(14.5%) |
1 |
11(20%) |
|
4~6 |
26(47.2%) |
23(41.8%) |
19(34.5%) |
22(40%) |
18(32.7%) |
2 |
23(41.8%) |
|
7~10 |
16(29%) |
4(7.3%) |
12(21.8%) |
25(45.5%) |
21(38.1%) |
3 |
15(27.2%) |
Table 3 : Score of clinical symptoms and signs before laser treatment
variables |
range, n(%) and Mean ± standard deviation. |
Three sessions |
41/55(74.5%) |
Four sessions |
10/55(18.1%) |
Five sessions |
4/55(7.2%) |
Average sessions |
3.3±0.6 |
Follow-ups |
3~12months |
Average follow-ups |
9.9±3.7 |
Table 4 : Number of laser treatment sessions, duration of laser procedure and follow-ups.
VAS |
Clinical signs |
Clinical symptoms |
||||
Vulvar itching |
Vulvar |
Dyspareunia |
Skin |
Skin |
Skin lesion Area |
|
Pre-operation |
5(4,7) |
3(2,5) |
3(1,6) |
6(3,8) |
6(4,7) |
2(1,2) |
1month after 1st operation |
4(3,5)a |
3(1,4)a |
4(1,6)c |
6(3,8)c |
6(4,7)c |
2(1,2)c |
1month after 3rd operation |
2(1,3)a |
1(0,2)a |
3(1,4)a |
6(3,8)c |
6(4,7)c |
2(0,2)a |
3months of follow-up |
1(0,1)a |
1(0,1)a |
3(1,4)a |
2(2,3)a |
6(4,7)c |
1(0,2)a |
6months of follow-up |
0(0,1)a |
0(0,1)a |
1(0,2)a |
2(2,3)a |
2(1,3)c |
1(0,2)a |
12months of follow-up |
0(0,1)a |
0(0,1)a |
1(0,1)a |
2(2,3)a |
2(1,2)b |
1(0,2)a |
Note: a = P <0.001;b = P <0.05;c = P>0.05.
Table 5 : multiple Comparisons of efficacy of VLS CO2 laser before and after treatment Expressed by median, upper and lower quartiles of VAS scores.
Tables at a glance
Figures at a glance